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镀锌笼具作为“渐弱婴儿”或“白猴”综合征发展中的一个潜在因素。

Galvanized caging as a potential factor in the development of the "fading infant" or "white monkey" syndrome.

作者信息

Obeck D K

出版信息

Lab Anim Sci. 1978 Dec;28(6):698-704.

PMID:108464
Abstract

Four rhesus females and their infants were kept in galvanized enclosures, and three were kept in stainless steel caging. All four offspring in the galvanized enclosures developed achromotrichia, alopecia, and weakness that varied from modererate to severe while the three infants in stainless steel cages were clinically normal. Plasma copper, zinc, and iron values as well as liver copper and zinc values of the infants were compared for the two types of caging. Plasma copper values were significantly lower (p less than 0.001) in the animals housed in galvanized cages. Plasma zinc and liver zinc levels were significantly elevated in these same animals (p less than 0.01 and p less than 0.05, respectively). Significant differences were not detected in liver copper values in the two groups of infants. Copper and zinc levels in the dams' plasma and milk were not statistically different between the two groups.

摘要

四只恒河猴雌性及其幼崽被饲养在镀锌围栏中,三只被饲养在不锈钢笼子里。镀锌围栏中的所有四只幼崽都出现了毛色变浅、脱发和程度从中度到重度不等的虚弱症状,而不锈钢笼子里的三只幼崽临床症状正常。对两种饲养环境下幼崽的血浆铜、锌、铁值以及肝脏铜和锌值进行了比较。饲养在镀锌笼子里的动物血浆铜值显著更低(p小于0.001)。这些动物的血浆锌和肝脏锌水平显著升高(分别为p小于0.01和p小于0.05)。两组幼崽的肝脏铜值未检测到显著差异。两组之间母猴血浆和乳汁中的铜和锌水平无统计学差异。

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Experientia. 1986 May 15;42(5):551-3. doi: 10.1007/BF01946698.