Sampson F C, Goodacre S, Kelly A-M, Kerr D
Medical Care Research Unit, University of Sheffield, Sheffield, S1 4DA, United Kingdom.
Emerg Med J. 2005 Nov;22(11):780-2. doi: 10.1136/emj.2004.020610.
Recent research has identified technologies that may be of value in the diagnosis and management of deep vein thrombosis (DVT). We aimed to survey current practice in the United Kingdom (UK) and Australia to determine the extent to which these technologies have been implemented in these two healthcare systems.
We undertook a postal survey of 255 hospitals in the UK and 89 hospitals in Australia, requesting details of individual diagnostic tests, use of diagnostic algorithms, and management of DVT.
We received replies from 186/255 UK hospitals (73%) and 84/89 of Australian hospitals (94%). Ultrasonography and laboratory based D-dimer were the most commonly available tests. We received 43 different algorithms from 51 hospitals. With only a very few exceptions, DVT diagnosis was ruled in by positive venography or positive ultrasound without venographic confirmation. By contrast a variety of different criteria were used to rule out DVT. Most algorithms used a combination of low clinical risk and negative D-dimer to rule out DVT, but some required all patients to receive ultrasound or venography. Few ruled out on the basis of low clinical risk or negative D-dimer alone. Low molecular weight heparins were overwhelmingly the treatment of choice for established DVT. Most departments (214/264; 81%) offered outpatient treatment.
Recently developed technologies for the diagnosis and treatment of DVT have been widely implemented in the UK and Australia. Variation in practice, and thus presumably uncertainty, seems to be greatest in relation with the criteria used to rule out DVT.
最近的研究已确定了一些可能对深静脉血栓形成(DVT)的诊断和管理有价值的技术。我们旨在调查英国(UK)和澳大利亚目前的实践情况,以确定这些技术在这两个医疗系统中的实施程度。
我们对英国的255家医院和澳大利亚的89家医院进行了邮寄调查,要求提供个体诊断测试的详细信息、诊断算法的使用情况以及DVT的管理情况。
我们收到了186/255家英国医院(73%)和84/89家澳大利亚医院(94%)的回复。超声检查和基于实验室的D-二聚体检测是最常用的检查。我们从51家医院收到了43种不同的算法。除极少数例外,DVT诊断通过阳性静脉造影或阳性超声且无需静脉造影确认来确定。相比之下,用于排除DVT的标准多种多样。大多数算法使用低临床风险和阴性D-二聚体的组合来排除DVT,但有些要求所有患者都接受超声或静脉造影检查。很少仅根据低临床风险或阴性D-二聚体来排除。低分子量肝素是已确诊DVT的压倒性首选治疗方法。大多数科室(214/264;81%)提供门诊治疗。
最近开发的DVT诊断和治疗技术已在英国和澳大利亚广泛实施。实践中的差异,因此可能存在的不确定性,似乎在用于排除DVT的标准方面最为明显。