Matuszewska Elzbieta, Miks Barbara, Grygalewicz Jacek, Załtska-Ponganis Joanna, Mordasewicz-Goliszewska Maria, Bełzecka Bozenna
Centrum Medycznego Kształcenia Podyplomowego, Warszawie.
Pol Merkur Lekarski. 2005 Aug;19(110):175-8.
The aim of this preliminary study was (1) to evaluate the usefulness of the Limulus amebocyte lysate (LAL) test as a diagnostic tool in pediatric clinic, and (2) to examine the serum ET levels in hospitalized patients.
Bacterial blood endotoxin (ET) was measured in 50 children with infections of different etiology and localization. A Limulus amebocyte lysate (LAL) test was used.
The usefulness of LAL test in routine diagnostic procedures in hospitalized children with infections was not proven so far. However, the LAL test appeared useful in the urinary tract infection (UTI) cases in which significant elevation of serum ET levels were demonstrated. Moreover, it was confirmed that LAL test can be performed as well in serum: the mean values of serum ET levels in our patients were comparable with published ET plasma values in adults.
本初步研究的目的是（1）评估鲎试剂检测在儿科临床作为诊断工具的实用性，以及（2）检测住院患者的血清内皮素（ET）水平。
对50例病因和感染部位不同的感染患儿进行细菌血内毒素（ET）检测。采用鲎试剂检测。
迄今为止，鲎试剂检测在住院感染患儿的常规诊断程序中的实用性尚未得到证实。然而，鲎试剂检测在血清内皮素水平显著升高的尿路感染（UTI）病例中似乎有用。此外，已证实鲎试剂检测也可在血清中进行：我们患者的血清内皮素水平平均值与已发表的成人血浆内皮素值相当。
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