Cianciulli Tomás E, Lax Jorge A, Beck Martín A, Cerruti Fausto E, Gigena Gerardo E, Saccheri Maria C, Fernández Eduardo, Dorelle Adriana N, Leguizamón Jorge H, Prezioso Horacio A
Echocardiography Laboratory, Division of Cardiology, Hospital del Gobierno de la Ciudad de Buenos Aires 'Dr. Cosme Argerich', Buenos Aires, Argentina.
J Heart Valve Dis. 2005 Sep;14(5):664-73.
Many types of mechanical prostheses are used for heart valve replacement, but it is difficult to distinguish between them using transthoracic echocardiography. Hence, cinefluoroscopy complements the echocardiographic evaluation of cardiac prostheses. The aims of the present study were to: (i) describe the contribution of cinefluoroscopy in identifying different prostheses; (ii) compare gradients obtained by Doppler echocardiography with the opening angle of the discs assessed by cinefluoroscopy; and (iii) assess the ability of cinefluoroscopy to distinguish normal from dysfunctional prostheses.
A total of 229 mechanical disc prostheses was prospectively evaluated with cinefluoroscopy. Eight prosthetic valves (six aortic, two mitral) were excluded due to the coexistence of severe left ventricular dysfunction. Thus, the final analysis comprised 221 prosthetic valves (146 aortic, 75 mitral).
Based on the characteristics of the ring and the discs, cinefluoroscopy identified 87 single-leaflet and 134 bileaflet prostheses. Disc motion allowed distinction to be made between normal and dysfunctional prostheses (opening angle: 74 +/- 13 degrees versus 49 +/- 18 degrees). Fluoroscopy could not define disc profile or the ring in 6% of aortic valves and in 26% of mitral prostheses. The technique could be used to identify the TriTechnologies and HP-Biplus valves, but could not provide data on prosthetic function due to radiolucency of the discs. Among the 146 aortic prostheses, Doppler echocardiography helped to identify 109 normal valves and 37 dysfunctional valves. Among 75 mitral prostheses, 54 normal and 21 dysfunctional prosthetic valves were identified. When both methods were correlated, the sensitivity, specificity and positive and negative predictive values of fluoroscopy to distinguish normal from malfunctioning prostheses were 83%, 80%, 89%, and 71%, respectively.
Each prosthesis type has radioscopic characteristics that allow its identification. Fluoroscopy permitted rapid and easy evaluation of mechanical prosthetic valve function, and in most cases allowed a distinction to be made between normal and dysfunctional prostheses. The presence of high gradients by Doppler echocardiography, with normal opening angles by fluoroscopy, and without pannus on transesophageal echocardiography, is indicative of patient-prosthesis mismatch. Fluoroscopy was superior to echocardiography in identifying disc motion, whilst Doppler study allowed the measurement of gradients and areas, and semiquantification of regurgitation. Thus, cinefluooscopy rapidly provides valuable information which is complementary to that obtained by echocardiography.
心脏瓣膜置换术使用多种类型的机械瓣膜,但经胸超声心动图难以区分这些瓣膜。因此,荧光透视检查可补充心脏瓣膜的超声心动图评估。本研究的目的是:(i)描述荧光透视检查在识别不同瓣膜方面的作用;(ii)比较多普勒超声心动图获得的压力阶差与荧光透视检查评估的瓣叶开放角度;(iii)评估荧光透视检查区分正常与功能障碍瓣膜的能力。
对229个机械瓣叶瓣膜进行前瞻性荧光透视检查评估。8个人工瓣膜(6个主动脉瓣、2个二尖瓣)因合并严重左心室功能不全被排除。因此,最终分析包括221个人工瓣膜(146个主动脉瓣、75个二尖瓣)。
根据瓣环和瓣叶的特征,荧光透视检查识别出87个单叶瓣膜和134个双叶瓣膜。瓣叶运动可区分正常与功能障碍瓣膜(开放角度:74±13度对49±18度)。荧光透视检查在6%的主动脉瓣和26%的二尖瓣中无法确定瓣叶形态或瓣环。该技术可用于识别TriTechnologies和HP-Biplus瓣膜,但由于瓣叶的射线可透性,无法提供有关瓣膜功能的数据。在146个主动脉瓣中,多普勒超声心动图有助于识别109个正常瓣膜和37个功能障碍瓣膜。在75个二尖瓣中,识别出54个正常人工瓣膜和21个功能障碍人工瓣膜。当两种方法进行关联分析时,荧光透视检查区分正常与功能异常瓣膜的敏感性、特异性、阳性预测值和阴性预测值分别为83%、80%、89%和71%。
每种瓣膜类型都有可用于识别的放射学特征。荧光透视检查可快速、简便地评估机械人工瓣膜功能,在大多数情况下可区分正常与功能障碍瓣膜。多普勒超声心动图显示高压力阶差、荧光透视检查显示开放角度正常且经食管超声心动图未显示赘生物,提示患者-人工瓣膜不匹配。在识别瓣叶运动方面,荧光透视检查优于超声心动图,而多普勒研究可测量压力阶差和面积,并对反流进行半定量分析。因此,荧光透视检查可迅速提供有价值的信息,补充超声心动图获得的信息。