Yalçin Funda, Yalçin Serhat, Berber Laçin, Gür Hasim
University of Istanbul, Faculty of Dentistry, Department of Periodontology, Turkey.
J Int Acad Periodontol. 2005 Oct;7(4):108-13.
Peripheral giant cell granuloma (PGCG) is a relatively uncommon benign tumor of the oral cavity affecting people of all ages and with no racial predilection. The etiology is still unclear but local trauma or chronic irritants may cause the development of this lesion. Hemangioma is a benign process in which there are an increased number of normal or abnormal-appearing blood vessels. In this article the clinical, radiographic and histopathologic characteristics of a patient who had a rare combination of PGCG and facial hemangioma is discussed. Surgery was the effective treatment modality for the lesion in the mandible. The characteristics of facial hemangioma and PGCG have similarities, such as the possibility of bleeding problems during surgery. As the lesion in this case was not small in size, it was not a conservative procedure. Bleeding control was established by electrocauterization. Healing was uneventful and there has been no recurrence since the surgery. A new prosthesis was fabricated for the patient. In these kinds of cases the control of bleeding must be very carefully determined and attention should be paid to the possibility of serious bleeding problems. Based on the data presented we were not able to find any correlation between the PGCG and the facial hemangioma, but new reports might have different views on the subject in the future.
外周巨细胞肉芽肿（PGCG）是一种相对罕见的口腔良性肿瘤，可发生于各年龄段人群，无种族倾向。其病因尚不清楚，但局部创伤或慢性刺激可能导致该病变的发生。血管瘤是一种良性病变，其中正常或外观异常的血管数量增多。本文讨论了一名患有PGCG与面部血管瘤罕见组合的患者的临床、影像学和组织病理学特征。手术是治疗下颌骨病变的有效方式。面部血管瘤和PGCG的特征有相似之处，比如手术过程中都有可能出现出血问题。由于该病例中的病变尺寸不小，因此并非保守治疗。通过电灼来控制出血。愈合过程顺利，自手术以来未出现复发情况。为患者制作了新的假体。在这类病例中，必须非常谨慎地确定出血控制方法，并应注意严重出血问题的可能性。基于所呈现的数据，我们未能发现PGCG与面部血管瘤之间存在任何关联，但未来新的报告可能对此主题有不同观点。
