Justus Timothy, Ravizza Susan M, Fiez Julie A, Ivry Richard B
University of California, Berkeley, CA, USA.
Brain Lang. 2005 Nov;95(2):304-18. doi: 10.1016/j.bandl.2005.02.001.
Ten cerebellar patients were compared to 10 control subjects on a verbal working memory task in which the phonological similarity of the words to be remembered and their modality of presentation were manipulated. Cerebellar patients demonstrated a reduction of the phonological similarity effect relative to controls. Further, this reduction did not depend systematically upon the presentation modality. These results first document that qualitative differences in verbal working memory may be observed following cerebellar damage, indicating altered cognitive processing, even though behavioral output as measured by the digit span may be within normal limits. However, the results also present problems for the hypothesis that the cerebellar role is specifically associated with articulatory rehearsal as conceptualized in the Baddeley-Hitch model of working memory.
将10名小脑病变患者与10名对照受试者进行比较,让他们完成一项言语工作记忆任务,在该任务中,对要记忆单词的语音相似性及其呈现方式进行了操控。与对照组相比,小脑病变患者表现出语音相似性效应降低。此外,这种降低并不系统地依赖于呈现方式。这些结果首次证明,小脑损伤后可能会观察到言语工作记忆的质性差异,这表明认知加工发生了改变,尽管数字广度测量的行为输出可能在正常范围内。然而,这些结果也给如下假设带来了问题,即小脑的作用与工作记忆的巴德利-希契模型中概念化的发音复述特别相关。