The sodium pump and hypertension: a physiological role for the cardiac glycoside binding site of the Na,K-ATPase.
作者信息
Kaplan Jack H
机构信息
Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Molecular Biology Research Building, 900 South Ashland Avenue, Chicago, IL 60607, USA.
出版信息
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15723-4. doi: 10.1073/pnas.0507965102. Epub 2005 Oct 24.
Abstract
摘要
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本文引用的文献
1
The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation.钠钾ATP酶高度保守的强心苷结合位点在血压调节中起作用。
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15845-50. doi: 10.1073/pnas.0507358102. Epub 2005 Oct 21.
2
The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart.钠钾ATP酶的α1亚型调节心脏收缩力，并在心脏中与钠钙交换体发生功能相互作用且共定位。
J Biol Chem. 2004 Dec 24;279(52):54053-61. doi: 10.1074/jbc.M410737200. Epub 2004 Oct 14.
3
The alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro.钠钾ATP酶的α2亚型介导哇巴因诱导的小鼠高血压，并在体外增加血管收缩性。
Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H477-85. doi: 10.1152/ajpheart.00083.2004. Epub 2004 Sep 30.
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Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.全国高血压防治联合委员会第七次报告：预防、检测、评估及治疗
Hypertension. 2003 Dec;42(6):1206-52. doi: 10.1161/01.HYP.0000107251.49515.c2. Epub 2003 Dec 1.
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The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice.钠钾ATP酶的α2亚型介导哇巴因诱导的小鼠心肌收缩力。
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6
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