苦霉素/甲基霉素聚酮合酶对天然和还原六酮底物的链延伸、大环内酯化及水解作用 - Suppr

Chain elongation, macrolactonization, and hydrolysis of natural and reduced hexaketide substrates by the picromycin/methymycin polyketide synthase.

作者信息

Wu Jiaquan, He Weiguo, Khosla Chaitan, Cane David E

机构信息

Department of Chemistry, Box H, Brown University, Providence, RI 02912-9108, USA.

出版信息

Angew Chem Int Ed Engl. 2005 Nov 25;44(46):7557-60. doi: 10.1002/anie.200502246.

DOI:10.1002/anie.200502246

PMID:16247819

Abstract

摘要

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Chain elongation, macrolactonization, and hydrolysis of natural and reduced hexaketide substrates by the picromycin/methymycin polyketide synthase.

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Chain elongation, macrolactonization, and hydrolysis of natural and reduced hexaketide substrates by the picromycin/methymycin polyketide synthase.

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Chain elongation, macrolactonization, and hydrolysis of natural and reduced hexaketide substrates by the picromycin/methymycin polyketide synthase.

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