Pauls D L, Crowe R R, Noyes R
J Affect Disord. 1979 Dec;1(4):387-90.
The Slater computational model for use in distinguishing between polygenic inheritance and the effects of a single dominant gene with incomplete penetrance was applied to 15 kindreds of anxiety neurosis (panic disorder). The number of observed unilateral pairs (two ancestral cases from one side of the kindred) was significantly greater than the number expected. Therefore, these results suggest a dominant mode of transmission for anxiety neurosis.
用于区分多基因遗传和具有不完全外显率的单一显性基因效应的斯莱特计算模型，被应用于15个焦虑神经症（惊恐障碍）家族。观察到的单侧配对数（来自家族一侧的两个先证病例）显著多于预期数量。因此，这些结果表明焦虑神经症存在显性遗传模式。
