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惊恐障碍家系的遗传学研究。

A genetic study of panic disorder pedigrees.

作者信息

Pauls D L, Bucher K D, Crowe R R, Noyes R

出版信息

Am J Hum Genet. 1980 Sep;32(5):639-44.

Abstract

Pedigree analysis is done on 19 kindreds of panic disorder, and the results suggest that this disorder is transmitted as an autosomal dominant trait. Seven of these 19 kindreds were ascertained through a panic disorder proband with mitral valve prolapse. When the analysis is done omitting these seven kindreds, the results also suggest that panic disorder without prolapse is transmitted as an autosomal dominant trait.

摘要

对19个惊恐障碍家系进行了系谱分析,结果表明该障碍以常染色体显性性状传递。这19个家系中有7个是通过患有二尖瓣脱垂的惊恐障碍先证者确定的。当分析时排除这7个家系,结果也表明无脱垂的惊恐障碍以常染色体显性性状传递。

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本文引用的文献

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Heredity in the Psychoneuroses (Summary).神经官能症中的遗传因素(总结)
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Anxiety states (anxiety neurosis): a review.焦虑状态(焦虑神经症):综述
J Nerv Ment Dis. 1973 Jan;156(1):3-18. doi: 10.1097/00005053-197301000-00001.
7
The evidence for genetic components in the neuroses. A review.神经症中遗传因素的证据。综述。
Arch Gen Psychiatry. 1973 Jul;29(1):111-8. doi: 10.1001/archpsyc.1973.04200010080014.

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