Lonergan G, Routsi E, Georgiadis T, Agelis G, Hondrelis J, Matsoukas J, Larsen L K, Caplan F R
Department of Chemistry, University of New Brunswick, Fredericton, Canada.
J Nat Prod. 1992 Feb;55(2):225-8. doi: 10.1021/np50080a012.
A sesquiterpene lactone, onopordopicrin [1], has been isolated from Centaurea sonchifolia. Its structure was established by 2D nmr (1H-1H and 13C-1H correlations), and the conformation in CHCl3 was examined by nOe studies. Cytotoxic, antibacterial, and antifungal activities are reported.
从苦苣菜（Centaurea sonchifolia）中分离出一种倍半萜内酯，即刺苞菊苦素[1]。通过二维核磁共振（1H-1H和13C-1H相关）确定了其结构，并通过核Overhauser效应（nOe）研究考察了其在氯仿中的构象。报道了其细胞毒性、抗菌和抗真菌活性。
