dfrA12 - orfF - aadA2 盒式阵列与 aadA1 基因盒之间的重组产生了一个杂合盒式结构，即 aadA8b。
Recombination between the dfrA12-orfF-aadA2 cassette array and an aadA1 gene cassette creates a hybrid cassette, aadA8b.
作者信息
Gestal Alicia M, Stokes H W, Partridge Sally R, Hall Ruth M
机构信息
Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia.
出版信息
Antimicrob Agents Chemother. 2005 Nov;49(11):4771-4. doi: 10.1128/AAC.49.11.4771-4774.2005.
Abstract
Homologous recombination between closely related gene cassettes, such as aadA1 and aadA2, which are 89% identical, can create hybrid cassettes and hybrids of existing cassette arrays. A new cassette array, dfrA12-orfF-aadA8b, which was created by such a recombination event occurring within the aadA2 cassette in the dfrA12-orfF-aadA2 array, has been identified.
摘要
密切相关的基因盒之间的同源重组，例如aadA1和aadA2，它们的序列相似度为89%，可以产生杂交基因盒以及现有基因盒阵列的杂交体。已鉴定出一种新的基因盒阵列dfrA12-orfF-aadA8b，它是由dfrA12-orfF-aadA2阵列中的aadA2基因盒内发生的此类重组事件产生的。
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