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1984年至2002年间在捷克共和国分离出的鼠伤寒沙门氏菌菌株中抗生素耐药性的演变

Evolution of antibiotic resistance in Salmonella enterica serovar typhimurium strains isolated in the Czech Republic between 1984 and 2002.

作者信息

Faldynova M, Pravcova M, Sisak F, Havlickova H, Kolackova I, Cizek A, Karpiskova R, Rychlik I

机构信息

Veterinary Research Institute, 621 32 Brno, Czech Republic.

出版信息

Antimicrob Agents Chemother. 2003 Jun;47(6):2002-5. doi: 10.1128/AAC.47.6.2002-2005.2003.

Abstract

In a collection of 66 Salmonella enterica serovar Typhimurium strains isolated between 1984 and 2002 in the Czech Republic, genes coding for antibiotic resistance were determined by using specific PCRs. We found that the pentadrug-resistant ACSSuT clone first appeared in the Czech Republic in 1990. A new variant of the aadA gene designated aadA21 is described, the 5' end of which was identical to aadA2 and the 3' end of which was identical to aadA1.

摘要

在1984年至2002年期间于捷克共和国分离出的66株肠炎沙门氏菌鼠伤寒血清型菌株中,通过使用特异性聚合酶链反应(PCR)来确定编码抗生素抗性的基因。我们发现,五重耐药ACSSuT克隆于1990年首次出现在捷克共和国。本文描述了一种名为aadA21的aadA基因新变体,其5'端与aadA2相同,3'端与aadA1相同。

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