Goldszmidt Eric, Kern Ralph, Chaput Alan, Macarthur Alison
Department of Anesthesia, Mount Sinai Hospital, Toronto, Ontario, Canada.
Can J Anaesth. 2005 Nov;52(9):971-7. doi: 10.1007/BF03022061.
We sought to determine the incidence, etiology, characteristics and risk factors for all headaches in the first week postpartum.
This was a prospective cohort study of 985 women delivering over a three-month period in a single tertiary-care institution. These women underwent a structured interview and follow-up to collect demographic data and to assess for the presence and characteristics of postpartum headache (PPHa) or neck/shoulder pain. All headaches were diagnosed using an algorithm based on the diagnostic criteria of the International Headache Society. Multivariate analysis was used to examine possible risk factors.
Three hundred eighty-one of the 985 study participants (39%) reported headaches or neck/shoulder pain during the study period. The median time to onset of the PPHa was two days (0, 6; 1st and 3rd quartiles) and duration was four hours (2, 24; 1st and 3rd quartiles). Primary headaches accounted for > 75% of PPHa. Only a small number of headaches (4%) were incapacitating. Postdural puncture headache accounted for 4.7% of all PPHa. Significant risk factors for the development of PPHa were: known inadvertent dural puncture [odds ratio (OR)adj = 6.36; 95% confidence interval (CI) 1.29, 31.24]; previous headache history (1-12/yr-OR(adj) = 1.57; 95% CI 1.01, 2.44; > 12/yr-OR(adj) = 2.25; 95% CI 1.63, 3.11); multiparity (OR(adj) = 1.37; 95% CI 1.03, 1.82) and increasing age (OR(adj) = 1.03/yr; 95% CI 1.00, 1.06).
Postpartum headaches are common, often first noted after discharge from hospital. The majority are related to primary headache disorders. Increased awareness of this epidemiological relationship and improved diagnosis of primary headache conditions may lead to improved headache-specific therapy and avoidance of unnecessary investigations or read-mission to hospital.
我们试图确定产后第一周所有头痛的发病率、病因、特征及危险因素。
这是一项对985名在单一三级医疗机构分娩的女性进行的前瞻性队列研究,研究为期三个月。这些女性接受了结构化访谈及随访,以收集人口统计学数据,并评估产后头痛(PPHa)或颈部/肩部疼痛的存在及特征。所有头痛均根据基于国际头痛协会诊断标准的算法进行诊断。采用多变量分析来检验可能的危险因素。
985名研究参与者中有381名(39%)在研究期间报告有头痛或颈部/肩部疼痛。PPHa的中位发病时间为两天(0,6;第1和第3四分位数),持续时间为4小时(2,24;第1和第3四分位数)。原发性头痛占PPHa的比例超过75%。只有少数头痛(4%)会使人丧失能力。硬膜外穿刺后头痛占所有PPHa的4.7%。PPHa发生的显著危险因素包括:已知意外硬膜穿刺[校正优势比(OR)adj = 6.36;95%置信区间(CI)1.29,31.24];既往头痛病史(每年1 - 12次 - OR(adj) = 1.57;95% CI 1.01,2.44;每年> 12次 - OR(adj) = 2.25;95% CI 1.63,3.11);多胎妊娠(OR(adj) = 1.37;95% CI 1.03,1.82)以及年龄增长(OR(adj) = 1.03/岁;95% CI 1.00,1.06)。
产后头痛很常见,通常在出院后首次出现。大多数与原发性头痛疾病有关。提高对这种流行病学关系的认识以及改善原发性头痛状况的诊断可能会带来更有针对性的头痛治疗,并避免不必要的检查或再次入院。