Fisher Laura H, Davies Michael J, Craig Timothy J
Department of Asthma, Allergy, and Immunology, The Pennsylvania State University, Milton S. Hershey Medical Center, Hershey, PA, USA.
Clin Rev Allergy Immunol. 2005 Oct;29(2):151-8. doi: 10.1385/CRIAI:29:2:151.
Rhinitis is a common condition that affects a significant proportion of the general population, as well as a high proportion of athletes. Nasal congestion is a predominate symptom of the late-phase reaction in allergic rhinitis and can have far-reaching effects that extend through the airway and beyond the nose. Rhinitis is often found in conjunction with asthma and is a risk factor for asthma. Nasal obstruction, which does not permit conditioning of inspired air by the nasal turbinates, may contribute to asthma symptoms and the development of asthma. These adverse conditions may be especially troublesome for the high-performance athlete who has increased nasal airflow turbulence and who competes under extreme conditions that may worsen rhinitis and asthma. Under the theory of the unified airway, an immune response induced in the nose may extend into the lungs via cytokines and other inflammatory mediators. Nasal congestion can significantly contribute to sleep dysfunction, leading to daytime fatigue and decreased performance. Treatment of allergic rhinitis can improve sleep and foster productivity. Control of rhinitis and nasal congestion, which is obtained by various therapies, may reverse lower airway tendency to bronchoconstriction.
鼻炎是一种常见病症,影响着相当一部分普通人群,以及很大比例的运动员。鼻充血是变应性鼻炎晚期反应的主要症状,可产生广泛影响,延伸至气道及鼻腔以外。鼻炎常与哮喘并发,是哮喘的一个危险因素。鼻阻塞使鼻甲无法对吸入空气进行调节,可能会导致哮喘症状及哮喘的发生。这些不良状况对于鼻腔气流紊乱加剧且在可能使鼻炎和哮喘恶化的极端条件下参赛的高水平运动员而言,可能尤其棘手。根据统一气道理论,鼻腔中引发的免疫反应可能会通过细胞因子和其他炎症介质扩散至肺部。鼻充血会显著导致睡眠功能障碍,进而引起日间疲劳及表现下降。变应性鼻炎的治疗可改善睡眠并提高工作效率。通过各种疗法控制鼻炎和鼻充血,可能会扭转下气道支气管收缩的趋势。