Mercurio Mark R
Department of Pediatrics (M.R.M.), Yale University School of Medicine, New Haven, CT 06520-8064, USA.
J Perinatol. 2005 Nov;25(11):685-9. doi: 10.1038/sj.jp.7211395.
Most neonatologists believe there is a minimal gestational age, below which it is appropriate to refuse to provide resuscitation or intensive care. Determination of this threshold should involve knowledge of the outcome data, but also an understanding of the potential for misuse of these data. In particular, there is a risk of deception, of the parents and of ourselves, due to the uncertainty of the true gestational age, and the "self-fulfilling prophecy" that may occur when a center refuses to try below a certain gestational age because they have had no survivors below that age. Finally, any refusal to treat requires ethical justification. Concepts such as futility and patient's best interest should play a role in the determination of the gestational age threshold, applied in light of the data's inherent weaknesses.
大多数新生儿科医生认为存在一个最低孕周,低于这个孕周拒绝提供复苏或重症监护是合适的。确定这个阈值不仅需要了解结局数据,还需要理解这些数据被滥用的可能性。特别是,由于真实孕周的不确定性,以及当一个中心因为在某个孕周以下没有存活者而拒绝在该孕周以下进行尝试时可能出现的“自我实现预言”,存在欺骗父母和我们自己的风险。最后,任何拒绝治疗都需要伦理依据。诸如无效性和患者最佳利益等概念应该在确定孕周阈值时发挥作用,鉴于数据固有的弱点来应用这些概念。