Cangini Filippo, Cornelini Roberto
J Periodontol. 2005 Oct;76(10):1785-92. doi: 10.1902/jop.2005.76.10.1785.
This clinical report compares the use of an enamel matrix derivative (EMD) and bioabsorbable barrier membrane to enhance healing following the immediate placement of transmucosal implants into extraction sockets.
Thirty-two adult patients scheduled for tooth replacement with dental implants agreed to participate. Following the insertion of a transmucosal implant into the extraction site, the subjects were assigned to one of two treatment alternatives of the remaining bone defects around the implants: 1) the residual bone defects were filled with EMD (EMD group) or 2) the residual bone defects were covered with a bioabsorbable membrane (membrane group). Flaps were then coronally positioned around implant cover screws. Patients followed weekly maintenance recalls for the first 6 weeks and then monthly recalls until the final prosthetic restoration was completed (after 6 months). The treatment outcome was evaluated after 12 months by the use of clinical variables. The null hypothesis of no treatment group differences was tested by the use of analysis of variance (ANOVA).
At a 12-month follow-up, all of the implants were completely osseointegrated and successfully functioning, showing a success rate of 100%. The membrane group showed a significantly lower mean probing attachment level than the EMD group at proximal (0.60 mm, standard deviation (SD) 0.37 versus 1.19 mm, SD 1.10), buccal (0.80 mm, SD 0.79 versus 1.77 mm, SD 1.16), and lingual sites (0.44 mm, SD 0.52 versus 1.48 mm, SD 1.46). The difference was statistically significant at all sites (P < 0.05). With respect to the position of the soft tissue margin around the implant shoulder, the membrane group showed a consistently higher value than the EMD group at, respectively, proximal (1.30 mm, SD 2.37 versus 1.16 mm, SD 1.0), buccal (0.90 mm, SD 1.29 versus 0.22 mm, SD 1.47), and lingual sites (1.12 mm, SD 1.10 versus 0.55 mm, SD 1.42).
The membrane group obtained more favorable results in terms of both the probing attachment level and peri-implant position of soft tissues compared to the EMD group. The use of a bioabsorbable membrane around immediately placed transmucosal implants enhanced soft and hard tissue healing and might be an advisable treatment choice particularly in areas with high esthetic demands.
本临床报告比较了使用釉基质衍生物(EMD)和生物可吸收屏障膜来促进经黏膜植入物即刻植入拔牙窝后的愈合情况。
32例计划用牙种植体进行牙齿修复的成年患者同意参与。在将经黏膜植入物插入拔牙部位后,受试者被分配到植入物周围剩余骨缺损的两种治疗方案之一:1)用EMD填充剩余骨缺损(EMD组)或2)用生物可吸收膜覆盖剩余骨缺损(膜组)。然后将瓣向冠方定位在种植体覆盖螺钉周围。患者在最初6周每周进行维护复诊,然后每月复诊,直至完成最终的修复体修复(6个月后)。12个月后通过临床变量评估治疗结果。使用方差分析(ANOVA)检验无治疗组差异的零假设。
在12个月的随访中,所有植入物均完全骨整合且功能正常,成功率为100%。膜组在近中(0.60 mm,标准差(SD)0.37 vs 1.19 mm,SD 1.10)、颊侧(0.80 mm,SD 0.79 vs 1.77 mm,SD 1.16)和舌侧部位(0.44 mm,SD 0.52 vs 1.48 mm,SD 1.46)的平均探诊附着水平显著低于EMD组。所有部位的差异均具有统计学意义(P < 0.05)。关于种植体肩部周围软组织边缘的位置,膜组在近中(1.30 mm,SD 2.37 vs 1.16 mm,SD 1.0)、颊侧(0.90 mm,SD 1.29 vs 0.22 mm,SD 1.47)和舌侧部位(1.12 mm,SD 1.10 vs 0.55 mm,SD 1.42)的值始终高于EMD组。
与EMD组相比,膜组在探诊附着水平和种植体周围软组织位置方面均获得了更有利的结果。在即刻植入的经黏膜植入物周围使用生物可吸收膜可促进软硬组织愈合,尤其在美学要求较高的区域可能是一种可取的治疗选择。