Weber Frank, Knopf Heinz
Department of Neurology of the German Air Force Institute of Aviation Medicine, PO Box 1264 KFL, D-82242 Fuerstenfeldbruck, Germany.
J Neurol Sci. 2006 Jan 15;240(1-2):81-4. doi: 10.1016/j.jns.2005.09.008. Epub 2005 Oct 26.
To determine the frequency of serious intracranial abnormalities in a healthy young male population.
Cranial MRI of 2,536 healthy young males, mean age 20.5 years, all applicants for military flying duties in the German Air Force.
The authors report a variety of morphological abnormalities in the brains of a large population of healthy young males, providing data on disease prevalence. Arachnoid cysts were found in 1.7% (95% CI 1.2 to 2.3%), vascular abnormalities in 0.51% (95% CI 0.29 to 0.9%), and intracranial tumors in 0.47% (95% CI 0.26 to 0.85%) of the applicants. No cerebral aneurysms were found.
The prevalence of primary brain tumors seems to be higher, whereas the prevalence of intracranial aneurysms is lower than expected. Only a small percentage of the detected abnormalities require urgent medical attention.
确定健康年轻男性人群中严重颅内异常的发生率。
对2536名健康年轻男性进行头颅MRI检查,这些男性均为德国空军军事飞行任务的申请者,平均年龄20.5岁。
作者报告了大量健康年轻男性大脑中存在多种形态学异常,提供了疾病患病率的数据。在申请者中,蛛网膜囊肿的发现率为1.7%(95%可信区间1.2%至2.3%),血管异常的发现率为0.51%(95%可信区间0.29%至0.9%),颅内肿瘤的发现率为0.47%(95%可信区间0.26%至0.85%)。未发现脑动脉瘤。
原发性脑肿瘤的患病率似乎较高,而颅内动脉瘤的患病率低于预期。所检测到的异常中只有一小部分需要紧急医疗关注。