Department of Radiology, University of California Davis School of Medicine, Sacramento, CA, USA.
Department of Neurology, University of California Davis School of Medicine, Sacramento, CA, USA.
J Neuroimaging. 2021 Nov;31(6):1166-1175. doi: 10.1111/jon.12910. Epub 2021 Jul 19.
There is limited literature on the prevalence of incidental brain MRI findings in the Hispanic/Latino population, despite their increased prevalence of vascular disease and undertreatment of chronic conditions. The purpose of our study was to determine the prevalence of clinically relevant incidental findings on brain MRI examinations obtained as a part of the Study of Latinos-Investigation of NeuroCognitive Aging MRI (SOL-INCA-MRI) study.
Brain MRI examinations were obtained on 1389 participants in the SOL-INCA-MRI study, a cross-sectional ancillary study of the Hispanic Community Health Study, Study of Latinos, which is a longitudinal, community-based study. Study design of SOL-INCA-MRI involves imaging cognitively normal and participants with mild cognitive impairment. Brain MRI findings were categorized as Level 1 (normal), Level 1.5 (findings of unclear medical significance), Level 2 (potential medical concern), or Level 3 (medically urgent). This article focuses on Level 2 and Level 3 findings.
The average age of the sample was 60.8 years (+/- 10.3 years), 66.1% were females. Level 2 and 3 findings were identified in 117 participants, (8.4%), of which 109 (7.8%) were recommended for medical follow-up (Level 2), and 8 (0.6%) were recommended for immediate medical attention (Level 3). Brain MRI findings consisted of chronic infarction in 33 (2.4%), vascular abnormality in 27 (1.9%), intracranial mass in 20 (1.4%), other intracranial findings in 28 (2.0%), and skull base/extracranial findings in 26 (1.9%) patients.
Incidental findings of clinical relevance were common among SOL-INCA-MRI participants, but rarely required urgent medical intervention.
尽管西班牙裔/拉丁裔人群的血管疾病发病率更高，且慢性病治疗不足，但关于其脑部磁共振成像（MRI）偶然发现的患病率的文献却很有限。我们的研究目的是确定作为拉丁裔社区健康研究-认知神经老化 MRI 研究（Hispanic Community Health Study-Investigation of NeuroCognitive Aging MRI，HCHS/SOLINCA-MRI）的一部分进行的脑部 MRI 检查中临床相关偶然发现的患病率。
HCHS/SOLINCA-MRI 是一项基于社区的拉丁裔纵向研究——拉丁裔社区健康研究的一项横断面辅助研究，共有 1389 名参与者接受了 SOLINCA-MRI 研究的脑部 MRI 检查。SOLINCA-MRI 的研究设计包括对认知正常和轻度认知障碍参与者进行成像。脑部 MRI 结果分为 1 级（正常）、1.5 级（检查结果意义不明）、2 级（可能存在医学关注）和 3 级（医学紧急）。本文重点介绍 2 级和 3 级发现。
该样本的平均年龄为 60.8 岁（+/-10.3 岁），66.1%为女性。117 名（8.4%）参与者存在 2 级和 3 级发现，其中 109 名（7.8%）建议进行医学随访（2 级），8 名（0.6%）建议立即进行医学关注（3 级）。脑部 MRI 结果包括 33 例（2.4%）慢性梗死、27 例（1.9%）血管异常、20 例（1.4%）颅内肿块、28 例（2.0%）其他颅内病变和 26 例（1.9%）颅骨基底/颅外病变。
SOLINCA-MRI 参与者中常见偶然发现具有临床意义的结果，但很少需要紧急医疗干预。
