Steinvorth Sarah, Corkin Suzanne, Halgren Eric
MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA.
Neuroimage. 2006 Mar;30(1):285-98. doi: 10.1016/j.neuroimage.2005.09.025. Epub 2005 Oct 28.
Ecphory occurs when one recollects a past event cued by a trigger, such as a picture, odor, or name. It is a central component of autobiographical memory, which allows us to "travel mentally back in time" and re-experience specific events from our personal past. Using fMRI and focusing on the role of medial temporal lobe (MTL) structures, we investigated the brain bases of autobiographical memory and whether they change with the age of memories. Importantly, we used an ecphory task in which the remote character of the memories was ensured. The results showed that a large bilateral network supports autobiographical memory: temporal lobe, temporo-parieto-occipital junction, dorsal prefrontal cortex, medial frontal cortex, retrosplenial cortex and surrounding areas, and MTL structures. This network, including MTL structures, changed little with the age of the memories.
当一个人在诸如图片、气味或名字等触发因素的提示下回忆过去的事件时，就会发生记忆唤起。它是自传体记忆的核心组成部分，使我们能够“在心理上回到过去”，重新体验个人过去的特定事件。我们使用功能磁共振成像（fMRI）并聚焦于内侧颞叶（MTL）结构的作用，研究了自传体记忆的脑基础以及它们是否随记忆的年龄而变化。重要的是，我们使用了一种能确保记忆具有久远特征的记忆唤起任务。结果表明，一个广泛的双侧网络支持自传体记忆：颞叶、颞顶枕交界处、背侧前额叶皮质、内侧额叶皮质、扣带回后皮质及周围区域，以及MTL结构。这个包括MTL结构的网络，随记忆的年龄变化很小。
