Gunasekara Ravindi, Chida Shahzad, Shahid Minahil, Begum Gulshan, Jolayemi Ayodeji
Psychiatry, Medical University of the Americas, Charlestown, KNA.
Psychiatry, Interfaith Medical Center, Brooklyn, USA.
Cureus. 2020 Dec 4;12(12):e11898. doi: 10.7759/cureus.11898.
We present an unusual case of a middle-aged patient with a near-total loss of autobiographical memory; the memory of one's own personal history and personal identity following a motor vehicle accident. The nature of his autobiographical memory loss was anterograde and retrograde amnesia, with the preservation of procedural learning, including an extensive set of medical skills, which he attributed to his career as a psychiatrist. Of significance was the absence of any traumatic changes in the medial temporal lobe structures, hippocampal formation, amygdala, and entorhinal cortex on brain imaging. The significance of our findings is discussed in the context of the evolving theories of the role of medial temporal lobe structures in memory formation.
我们报告了一例不寻常的病例，一名中年患者在机动车事故后自传体记忆几乎完全丧失，即对自己个人经历和个人身份的记忆丧失。他自传体记忆丧失的性质是顺行性和逆行性失忆，程序性学习得以保留，包括一系列广泛的医疗技能，他将其归因于自己作为精神科医生的职业经历。重要的是，脑部成像显示内侧颞叶结构、海马结构、杏仁核和内嗅皮质没有任何创伤性变化。我们结合内侧颞叶结构在记忆形成中作用的不断发展的理论来讨论我们研究结果的意义。
