Molnár Ildikó
Hajdú-Bihar Megyei Onkormányzat, Kenézy Gyula Kórház-Rendelointézet, 111. Belgyógyászat, Debrecen.
Orv Hetil. 2005 Oct 2;146(40):2067-72.
Cardiovascular consequences of thyroid diseases, their prevalence and treatment, particularly in cases with subclinical hyper- and hypothyroidism. The aim of the study was to draw attention to an association between the thyroid and cardiovascular diseases. The main topic was to lay emphasis on the importance of cardiovascular diseases caused by subclinical hyper- and hypothyroidism in the relation to the practice. The subclinical states precede the overt hyper- and hypothyroidism, and they are often present during their treatments. The changes in the levels of thyrotropin demonstrating subclinical thyroid diseases, could be detected in different non-thyroid diseases and resulted from the effect of some drugs. Particularly, the subclinical thyroid diseases become more frequent in older age. In the background of the high prevalences of atrial fibrillation, hypertension and psychosomatic events subclinical hyperthyroidism could be revealed. Subclinical hypothyroidism is characterized by an increased prevalence of elevated serum lipid levels, atherosclerosis, ischemic heart disease and hypertension often associating with the presence of anti-thyroid antibodies. It is important to reveal subclinical thyroid diseases in time for the effective treatment and for stopping of the cardiovascular damages before manifestations of cardiovascular diseases. The paper gives advice for the practice and the rational management. At the end, a survey of the association between thyroid and heart diseases in own department of internal medicine at the last three years is given.
甲状腺疾病的心血管后果、其患病率及治疗,尤其在亚临床甲状腺功能亢进和减退病例中的情况。本研究的目的是引起人们对甲状腺与心血管疾病之间关联的关注。主要主题是强调亚临床甲状腺功能亢进和减退所致心血管疾病在临床实践中的重要性。亚临床状态先于明显的甲状腺功能亢进和减退出现,且在治疗过程中也常常存在。在不同的非甲状腺疾病中可检测到表明亚临床甲状腺疾病的促甲状腺激素水平变化,这些变化是由某些药物的作用导致的。特别是,亚临床甲状腺疾病在老年人中更为常见。在心房颤动、高血压和心身事件高发的背景下可发现亚临床甲状腺功能亢进。亚临床甲状腺功能减退的特征是血清脂质水平升高、动脉粥样硬化、缺血性心脏病和高血压的患病率增加,且常与抗甲状腺抗体的存在相关。及时发现亚临床甲状腺疾病对于有效治疗以及在心血管疾病表现出来之前阻止心血管损害至关重要。本文为临床实践和合理管理提供了建议。最后,给出了过去三年本内科自身科室甲状腺与心脏病之间关联的一项调查。