[Mechanism of changes in renal functions in osmotic irritation of the right atrium].

Chronic experiments conducted on 17 dogs whose ureters were brought out on the skin of the abdomen showed that administration of solutions of saccharose (1150 mmol/l) and NaCl (515 mmol/l) into the right atrium reduces diuresis and increases natriuresis. The concentration of atrial natriuretic factor in the blood does not change, vasopressin and cortisol secretion increases while that of aldosterone decreases. It is concluded that, in addition to the cardiopeptide mechanism regulating the blood volume, the right atrium possesses a reflex osmoregulatory mechanism.