Krasnova E E, Chemodanova V V, Klykova E N
Eksp Klin Gastroenterol. 2004(6):84-8, 165.
The goal of the research was to study the peculiarities of adhesion and migration characteristics of leukocytes in children with chronic gastroduodenitis as compared to patients with functional dyspepsia and healthy children. An increase in the values of spontaneous adhesion and migration was noted in lymphocytes, monocytes and neutrophils during the exacerbation period of gastroduodenitis, which correlates with clinical manifestations, data of the morphological study and intragastric pH-metry. At the same time, a reduction in the functional reserve of leukocytes and their sensibility to adhesion stimulators. The dynamics of the examined characteristics was determined after the treatment. The results obtained are the evidence of the possibility to use the parameters of adhesion and migration capabilities of leukocytes for diagnosing chronic gastroduodenitis.
该研究的目的是，与功能性消化不良患者及健康儿童相比，研究患有慢性胃十二指肠炎症的儿童白细胞的黏附及迁移特性。在胃十二指肠炎症的发作期，淋巴细胞、单核细胞及中性粒细胞的自发黏附及迁移值增加，这与临床表现、形态学研究数据及胃内pH测量相关。与此同时，白细胞的功能储备及其对黏附刺激物的敏感性降低。治疗后测定了所检查特性的动态变化。所获结果证明了利用白细胞黏附及迁移能力参数诊断慢性胃十二指肠炎症的可能性。
