Kwong F N K, Ibrahim T, Power R A
Department of Orthopaedic Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Groby Road, Leicester LE3 9QP, UK.
J Bone Joint Surg Br. 2005 Nov;87(11):1524-6. doi: 10.1302/0301-620X.87B11.16354.
Implantation of allograft bone is an integral part of revision surgery of the hip. One major concern with its use is the risk of transmission of infective agents. There are a number of methods of processing allograft bone in order to reduce this risk. One method requires washing the tissue using pulsed irrigation immediately before implantation. We report the incidence of deep bacterial infection in 138 patients (144 revision hip arthroplasties) who had undergone implantation of allograft bone. The bone used was fresh-frozen, non-irradiated and pulse-washed with normal saline before implantation. The deep infection rate at a minimum follow-up of one year was 0.7%. This method of processing appears to be associated with a very low risk of allograft-related bacterial infection.
同种异体骨植入是髋关节翻修手术的一个重要组成部分。使用同种异体骨的一个主要担忧是感染因子传播的风险。为了降低这种风险，有多种处理同种异体骨的方法。一种方法是在植入前立即使用脉冲冲洗来清洗组织。我们报告了138例（144例髋关节翻修置换术）接受同种异体骨植入患者深部细菌感染的发生率。所用的骨是新鲜冷冻、未辐照且在植入前用生理盐水进行脉冲冲洗的。至少随访一年时的深部感染率为0.7%。这种处理方法似乎与同种异体骨相关细菌感染的极低风险相关。
