Unal D, Millet V, LeClaire M, Bartoli J M, Boubli L, Gamerre M, Blanc B
Maternité de la Belle de Mai, Marseille.
Rev Fr Gynecol Obstet. 1992 May;87(5):283-7.
Twenty-six cases of premature braking of the membranes which occurred before week 34 of amenorrhea and lasted for more than 5 days are assessed retrospectively. The mean age when the membranes broke was 26.6 weeks of amenorrhea. Delivery occurred on average at 31.5 +/- 2 WA, with an interval of between 6 and 91 days (mean 35 +/- 23 days). In 4 cases, chorioamniotitis complicated the premature breaking of the membranes. The perinatal mortality rate was 5 out of 27, including 2 still births. Nine of the neonates showed respiratory distress which required artificial ventilation. Four cases of pulmonary hypoplasia were confirmed by pathological examination. In all cases, this was associated with a reduction in the volume of the amniotic fluid, reduced fetal mobility and delayed intrauterine growth. In contrast, when these three factors were absent the prognosis was always good, regardless of the date at which the membranes broke. In the long term, the surviving children showed no neurological sequelae.
对26例在闭经34周前发生胎膜早破且持续超过5天的病例进行回顾性评估。胎膜破裂时的平均年龄为闭经26.6周。分娩平均发生在31.5±2周龄，间隔时间为6至91天（平均35±23天）。4例发生绒毛膜羊膜炎并发胎膜早破。围产期死亡率为27例中有5例，其中包括2例死产。9例新生儿出现呼吸窘迫，需要人工通气。经病理检查确诊4例肺发育不全。在所有病例中，这均与羊水过少、胎儿活动减少和宫内生长迟缓有关。相比之下，当不存在这三个因素时，无论胎膜破裂日期如何，预后总是良好的。从长远来看，存活儿童未出现神经后遗症。
