Pehrsson K, Nachemson A, Olofson J, Ström K, Larsson S
Department of Lung Medicine, University of Göteborg, Sweden.
Spine (Phila Pa 1976). 1992 Jun;17(6):714-8. doi: 10.1097/00007632-199206000-00012.
Registers covering Swedish patients with home ventilator or long-term oxygen therapy were used to study respiratory failure caused by thoracic deformities. In all, 107 patients were studied. Postpolio scoliosis was found in 47 patients. The age of starting therapy varied between 28 and 80 years. Fourteen patients had thoracic deformities other than scoliosis. The mean scoliotic angle was 135 degrees among the patients with scoliosis, and the mean vital capacity was 26% (range, 13-54%) of predicted normal. The yearly demand for home ventilator or oxygen therapy is calculated to three per million inhabitants. No operated patients had respiratory failure, and no patients were found with idiopathic scoliosis and respiratory failure younger than 30 years of age, which may indicate a preventive effect of corrective surgery on the development of respiratory failure.
研究胸廓畸形所致呼吸衰竭时，使用了涵盖瑞典接受家庭通气或长期氧疗患者的登记资料。总共研究了107例患者。47例患者存在脊髓灰质炎后脊柱侧弯。开始治疗的年龄在28至80岁之间。14例患者有除脊柱侧弯以外的胸廓畸形。脊柱侧弯患者的平均脊柱侧弯角度为135度，平均肺活量为预测正常值的26%（范围为13%-54%）。家庭通气或氧疗的年需求经计算为每百万居民中有3例。接受手术的患者均未出现呼吸衰竭，且未发现年龄小于30岁的特发性脊柱侧弯合并呼吸衰竭患者，这可能表明矫正手术对呼吸衰竭的发展有预防作用。
