Rigatelli Gianluca, Baratto Adriano, Panin Stefano, Bedendo Emiliano, Bader Giovanni, Rigatelli Giorgio
EndoCardioVascular Therapy Research, Legnago, 37040 Verona, Italy.
Cardiovasc Revasc Med. 2005 Apr-Jun;6(2):48-51. doi: 10.1016/j.carrev.2005.05.001.
Although the most widely used screening techniques for extracardiac atherosclerotic distributions are noninvasive, in patients undergoing coronary arteriography, the question as to whether angiography of extracardiac arteries at the time of cardiac catheterization is really effective or if it should be considered malpractice is still open. We sought to determine the safety and real usefulness of angiography of extracardiac arteries performed by trained invasive cardiologists during cardiac catheterization.
Medical records of all patients undergoing combined coronary and noncoronary angiography between May 1998 and December 2002 were retrospectively reviewed. Moderate to severe arterial stenosis (>50% stenosis), vessel occlusion, aneurysmal, or severe ectasia were noted as significant angiographic findings.
Two hundred and seventy patients (165 males, mean age = 67.7+/-9.2 years, mean serum creatinine = 1.1+/-0.8 mg/dl) underwent combined cardiac catheterization and angiography of extracardiac arteries following specific indications. Significant findings were reported in 66 (24.4%) patients. Logistic regression analyses revealed three-vessel coronary artery disease [CAD; odds ratio (OR)=9.917; 95% confidence interval (CI) = 2.2 to 43.8; P = .002) and hypercholesterolemia (OR = 2.851; 95% CI=1.03 to 7.9; P = .044) to be independent predictors of extracardiac atherosclerotic involvement. Complications rate was negligible. The detection of significant angiographic findings led to endovascular treatment in 37.8% and surgical vascular repair in 33.3% of cases.
Angiography of extracardiac arteries at the time of coronary angiography appears justified only in patients with specific indications, multivessel CAD, and hypercholesterolemia.
尽管用于筛查心外动脉粥样硬化分布的最广泛使用的技术是非侵入性的,但对于接受冠状动脉造影的患者,在心脏导管插入术时进行心外动脉造影是否真的有效,或者是否应被视为医疗事故,这个问题仍然没有定论。我们试图确定由训练有素的介入心脏病专家在心脏导管插入术期间进行的心外动脉造影的安全性和实际效用。
回顾性分析1998年5月至2002年12月期间所有接受冠状动脉和非冠状动脉联合造影的患者的病历。中度至重度动脉狭窄(狭窄>50%)、血管闭塞、动脉瘤或严重扩张被记录为显著的血管造影结果。
270例患者(165例男性,平均年龄=67.7±9.2岁,平均血清肌酐=1.1±0.8mg/dl)在特定指征下接受了心脏导管插入术和心外动脉造影。66例(24.4%)患者报告有显著发现。逻辑回归分析显示三支血管冠状动脉疾病[CAD;优势比(OR)=9.917;95%置信区间(CI)=2.2至43.8;P=.002]和高胆固醇血症(OR=2.851;95%CI=1.03至7.9;P=.044)是心外动脉粥样硬化累及的独立预测因素。并发症发生率可忽略不计。在37.8%的病例中,显著血管造影结果的检测导致了血管内治疗,在33.3%的病例中导致了外科血管修复。
仅在有特定指征、多支血管CAD和高胆固醇血症的患者中,冠状动脉造影时进行心外动脉造影似乎是合理的。