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造血干细胞移植后的急性肺损伤

Acute lung injury after hematopoietic stem cell transplantation.

作者信息

Peters Steve G, Afessa Bekele

机构信息

Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

出版信息

Clin Chest Med. 2005 Dec;26(4):561-9, vi. doi: 10.1016/j.ccm.2005.06.009.

Abstract

Hematopoietic stem cell transplantation (HSCT) has emerged as a common therapeutic option for a variety of life-threatening disorders, especially hematologic malignancies. Pulmonary complications are reported in 30% to 60% of all recipients and represent a major cause of mortality. A major proportion of these complications are the direct result of infection. This article addresses early, noninfectious causes of acute lung injury in the HSCT recipient.

摘要

造血干细胞移植(HSCT)已成为治疗各种危及生命疾病的常见选择,尤其是血液系统恶性肿瘤。据报道,30%至60%的受者会出现肺部并发症,这是导致死亡的主要原因。这些并发症的很大一部分是感染的直接结果。本文探讨造血干细胞移植受者急性肺损伤的早期非感染性病因。

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