Peters Steve G, Afessa Bekele
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
Clin Chest Med. 2005 Dec;26(4):561-9, vi. doi: 10.1016/j.ccm.2005.06.009.
Hematopoietic stem cell transplantation (HSCT) has emerged as a common therapeutic option for a variety of life-threatening disorders, especially hematologic malignancies. Pulmonary complications are reported in 30% to 60% of all recipients and represent a major cause of mortality. A major proportion of these complications are the direct result of infection. This article addresses early, noninfectious causes of acute lung injury in the HSCT recipient.
造血干细胞移植(HSCT)已成为治疗各种危及生命疾病的常见选择,尤其是血液系统恶性肿瘤。据报道,30%至60%的受者会出现肺部并发症,这是导致死亡的主要原因。这些并发症的很大一部分是感染的直接结果。本文探讨造血干细胞移植受者急性肺损伤的早期非感染性病因。