呼吸道源和肠道源猫杯状病毒毒株对胆汁的稳定性差异。
Different stabilities to bile among feline calicivirus strains of respiratory and enteric origin.
作者信息
Mochizuki M
机构信息
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, Japan.
出版信息
Vet Microbiol. 1992 Jun 1;31(2-3):297-302. doi: 10.1016/0378-1135(92)90087-a.
Abstract
Feline calicivirus (FCV) strains isolated from feces (E-FCV) were compared with FCV strains of respiratory origin (R-FCV). All strains were shown to be labile at pH 3.0. All strains except one strain of E-FCV were found to be sensitive to the action of trypsin. When exposed to bile salt (deoxycholic acid sodium salt), all R-FCV strains were markedly inactivated, but none of the E-FCV strains was inactivated. It was possible to select bile-resistant substrains from a bile-sensitive strain.
摘要
将从粪便中分离出的猫杯状病毒（FCV）毒株（E-FCV）与呼吸道来源的FCV毒株（R-FCV）进行了比较。所有毒株在pH 3.0时均显示不稳定。除一株E-FCV毒株外，所有毒株均对胰蛋白酶的作用敏感。当暴露于胆盐（脱氧胆酸钠盐）时，所有R-FCV毒株均被显著灭活，但E-FCV毒株均未被灭活。从一株对胆汁敏感的毒株中有可能筛选出耐胆汁的亚毒株。
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