O'Conner Angus R, Franc Benjamin L
Department of Radiology, Nottingham City Hospital, UK.
Nucl Med Commun. 2005 Dec;26(12):1107-11. doi: 10.1097/00006231-200512000-00010.
To assess the usefulness of fluorodeoxyglucose positron emission tomography (FDG PET) in the evaluation of post-transplant lymphoproliferative disorder (PTLD) following renal transplantation.
Staging FDG PET examinations were reviewed in five patients with biopsy proven post-renal allograft PTLD and compared with conventional imaging. Follow-up PET examinations of three patients at various points during their therapy for PTLD were also reviewed and compared with clinical outcome.
PET imaging identified all disease sites seen at cross-sectional imaging, clarified sites of uncertain significance and detected additional disease in two out of five patients. Early follow-up imaging impacted PTLD management in two of three patients.
In this limited series FDG PET was an effective imaging modality in the staging and follow-up of PTLD.
评估氟脱氧葡萄糖正电子发射断层扫描（FDG PET）在肾移植后移植后淋巴增殖性疾病（PTLD）评估中的作用。
回顾了5例经活检证实为肾移植后PTLD患者的分期FDG PET检查，并与传统成像进行比较。还回顾了3例PTLD患者在治疗期间不同时间点的随访PET检查，并与临床结果进行比较。
PET成像识别出横断面成像所见的所有病灶，明确了意义不确定的部位，并在5例患者中的2例检测到额外病灶。早期随访成像影响了3例患者中2例的PTLD治疗。
在这个有限的系列研究中，FDG PET是PTLD分期和随访的有效成像方式。
