氟代脱氧葡萄糖正电子发射断层扫描成像在肾移植后移植后淋巴组织增生性疾病评估中的应用
FDG PET imaging in the evaluation of post-transplant lymphoproliferative disorder following renal transplantation.
作者信息
O'Conner Angus R, Franc Benjamin L
机构信息
Department of Radiology, Nottingham City Hospital, UK.
出版信息
Nucl Med Commun. 2005 Dec;26(12):1107-11. doi: 10.1097/00006231-200512000-00010.
OBJECTIVES
To assess the usefulness of fluorodeoxyglucose positron emission tomography (FDG PET) in the evaluation of post-transplant lymphoproliferative disorder (PTLD) following renal transplantation.
METHODS
Staging FDG PET examinations were reviewed in five patients with biopsy proven post-renal allograft PTLD and compared with conventional imaging. Follow-up PET examinations of three patients at various points during their therapy for PTLD were also reviewed and compared with clinical outcome.
RESULTS
PET imaging identified all disease sites seen at cross-sectional imaging, clarified sites of uncertain significance and detected additional disease in two out of five patients. Early follow-up imaging impacted PTLD management in two of three patients.
CONCLUSION
In this limited series FDG PET was an effective imaging modality in the staging and follow-up of PTLD.
目的
评估氟脱氧葡萄糖正电子发射断层扫描（FDG PET）在肾移植后移植后淋巴增殖性疾病（PTLD）评估中的作用。
方法
回顾了5例经活检证实为肾移植后PTLD患者的分期FDG PET检查，并与传统成像进行比较。还回顾了3例PTLD患者在治疗期间不同时间点的随访PET检查，并与临床结果进行比较。
结果
PET成像识别出横断面成像所见的所有病灶，明确了意义不确定的部位，并在5例患者中的2例检测到额外病灶。早期随访成像影响了3例患者中2例的PTLD治疗。
结论
在这个有限的系列研究中，FDG PET是PTLD分期和随访的有效成像方式。
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