氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在腹部移植后淋巴组织增生性疾病中的应用
FDG-PET/CT in abdominal post-transplant lymphoproliferative disease.
作者信息
Metser Ur, Lo Glen
机构信息
Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital and Women's College Hospital, University of Toronto, Toronto, ON, Canada.
出版信息
Br J Radiol. 2016;89(1057):20150844. doi: 10.1259/bjr.20150844. Epub 2015 Nov 6.
Abstract
Post-transplant lymphoproliferative disease (PTLD) is a major cause of morbidity and mortality following both solid organ and haematopoietic stem cell transplantation. PTLD has a broad range of manifestations with extranodal involvement more common in the abdomen than nodal involvement. Fludeoxyglucose positron emission tomography/CT (FDG-PET/CT) is sensitive and specific to detect PTLD and can upstage or detect occult PTLD compared with conventional CT imaging. As functional imaging, FDG-PET/CT also has a role in monitoring treatment response. In this pictorial essay, we will discuss the role of FDG-PET/CT in the diagnosis and staging of abdominal PTLD and describe the advantages of functional imaging in assessing response to therapy.
摘要
移植后淋巴细胞增生性疾病（PTLD）是实体器官移植和造血干细胞移植后发病和死亡的主要原因。PTLD有广泛的表现，结外受累在腹部比淋巴结受累更常见。氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）对检测PTLD敏感且特异，与传统CT成像相比，可使PTLD分期升高或检测出隐匿性PTLD。作为功能成像，FDG-PET/CT在监测治疗反应方面也有作用。在这篇影像论文中，我们将讨论FDG-PET/CT在腹部PTLD诊断和分期中的作用，并描述功能成像在评估治疗反应中的优势。
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