Olsen Kristina I, Schroeder Paul, Corby Rod, Vucic Ivica, Bardo Dianna M E
Department of Neuroradiology, The University of Chicago, 5841 S. Maryland Ave., MC 2026, Chicago, IL 60637, USA.
Expert Rev Neurother. 2005 Nov;5(6 Suppl):S3-11. doi: 10.1586/14737175.5.6.S3.
To make full use of the benefits of magnetic resonance imaging (MRI) in the evaluation of intracranial glioma, a variety of advanced MRI and qualitative and quantitative techniques can be added to the radiologists' diagnostic armamentarium, beyond the standard contrast-enhanced images. These techniques include perfusion MRI, which is useful in the characterization of glioma because a relative quantification of cerebral microcirculatory parameters may be estimated; magnetic resonance spectroscopy, which can provide an estimate of the concentration of normal and abnormal metabolites in the brain and, when supplemented with magnetic resonance perfusion data, can be a useful tool for distinguishing between tumor recurrence and radiation necrosis; and diffusion tensor imaging, which combines physiologic behaviors unique to the cytoarchitecture of brain cells and the interstitial tissues with 2D and 3D anatomic magnetic resonance images, and thereby differentiates intact white matter tracts, displaced by tumor or surrounding edema, from invasion or disruption by a more aggressive neoplasm.
为了充分利用磁共振成像（MRI）在评估颅内胶质瘤方面的优势，除了标准的对比增强图像外，放射科医生的诊断手段中还可以增加各种先进的MRI以及定性和定量技术。这些技术包括灌注MRI，它对胶质瘤的特征描述很有用，因为可以估计脑微循环参数的相对定量；磁共振波谱分析，它可以估计大脑中正常和异常代谢物的浓度，并且当与磁共振灌注数据相结合时，可成为区分肿瘤复发和放射性坏死的有用工具；以及扩散张量成像，它将脑细胞和间质组织细胞结构特有的生理行为与二维和三维解剖磁共振图像相结合，从而区分因肿瘤或周围水肿而移位的完整白质束与侵袭性更强的肿瘤的侵犯或破坏。
