Bastani Roshan, Maxwell Annette E, Kagawa-Singer Marjorie, Glenn Beth A, Parada Koy
University of California Los Angeles School of Public Health and Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095-6900, USA.
Cancer. 2005 Dec 15;104(12 Suppl):2926-30. doi: 10.1002/cncr.21517.
The landmark Institute of Medicine Report on the "Unequal Burden of Cancer" urgently called for efforts to reduce cancer disparities by conducting research that could rapidly translate laboratory and clinical findings to benefit large segments of society. It also called for intensifying efforts to produce well-trained minority researchers as a way to increase the quantity, quality and community relevance of cancer control research. This manuscript summarized our strategies and successes in these two areas. Over a five year period, the Los Angeles site of the NCI-funded Asian American Network for Cancer Awareness, Research, and Training (AANCART-LA) conducted intensive community based cancer awareness activities through a coalition of over 20 Asian serving community organizations. In addition, a major focus of AANCART-LA was on increasing community-relevant research and on training scientists to conduct research among Asians. Strategies to reach these goals included a focus on pilot studies as a way of introducing the community to research, selection of promising junior scientists to submit applications for pilot funding, and close mentoring of these individuals by seasoned investigators. We describe four pilot project proposals that were selected for funding by the NCI peer review process. In addition, AANCART-LA was able to obtain peer reviewed funding for several other research projects targeting a variety of Asian sub-groups. These projects were the direct outcome of extensive cancer awareness activities in the community, the publicity associated with receiving peer-reviewed pilot project funding, and the collaborations established with multiple community based organizations.
具有里程碑意义的医学研究所关于“癌症负担不平等”的报告紧急呼吁,通过开展能迅速将实验室和临床研究结果转化应用以造福广大社会群体的研究,来努力减少癌症差异。该报告还呼吁加大力度培养训练有素的少数族裔研究人员,以此增加癌症控制研究的数量、质量及与社区的相关性。本手稿总结了我们在这两个领域的策略与成果。在五年时间里,由美国国立癌症研究所资助的亚裔美国人癌症意识、研究与培训网络洛杉矶分部(AANCART-LA),通过20多个服务亚裔的社区组织联盟开展了密集的社区癌症意识活动。此外,AANCART-LA的一个主要重点是增加与社区相关的研究,并培训科学家在亚裔群体中开展研究。实现这些目标的策略包括专注于试点研究,以此向社区介绍研究;挑选有前途的初级科学家提交试点资金申请,并由经验丰富的研究人员对这些人员进行密切指导。我们描述了四个通过美国国立癌症研究所同行评审程序被选中获得资助的试点项目提案。此外AANCART-LA还为其他几个针对不同亚裔亚群体的研究项目获得了同行评审资金。这些项目是社区广泛开展癌症意识活动、获得同行评审试点项目资金所带来的宣传效应,以及与多个社区组织建立合作关系的直接成果。