Department of Nuclear Medicine and PET Research, VU University Medical Centre, Amsterdam, The Netherlands.
Clin Res Cardiol. 2010 Aug;99(8):475-81. doi: 10.1007/s00392-010-0159-1. Epub 2010 Apr 21.
There is no consensus regarding the definition of cardiac syndrome X (CSX). We systematically reviewed recent literature using a standardized search strategy. We included 57 articles. A total of 47 studies mentioned a male/female distribution. A meta-analysis yielded a pooled proportion of females of 0.56 (n = 1,934 patients, with 95% confidence interval: 0.54-0.59). As much as 9 inclusion criteria and 43 exclusion criteria were found in the 57 articles. Applying these criteria to a population with normal coronary angiograms and treated in 1 year at a general hospital, the attributable CSX incidence varied between 3 and 11%. The many inclusion and exclusion criteria result in a wide range of definitions of CSX and these have large effects on the incidence. This shows the need for a generally accepted definition of CSX.
目前对于心脏 X 综合征（CSX）尚没有统一的定义。我们采用标准化的检索策略对近期文献进行了系统回顾，共纳入 57 篇文献。其中，47 篇文献报道了男女发病比例，荟萃分析结果显示女性患者的比例为 0.56（n=1934 例，95%置信区间：0.54-0.59）。57 篇文献中纳入标准多达 9 项，排除标准多达 43 项。如果将这些标准应用于冠状动脉造影正常且在综合医院治疗 1 年的人群，归因于 CSX 的发生率在 3%至 11%之间。如此多的纳入和排除标准导致 CSX 的定义范围很广，这对其发生率有很大影响。这表明需要对 CSX 有一个普遍接受的定义。
