Nagasawa H, Amano K, Araki M
Experimental Animal Research Laboratory, Meiji University, Kanagawa, Japan.
In Vivo. 1992 Jan-Feb;6(1):69-71.
The partial correlation coefficients were computed between pup growth rate on day 12 of lactation and mother weight on day 11 or daily food or water intake by mother between days 4 and 11 in the 1st to 3rd lactations of four strains of mice, SHN, SLN, C3H/He and GR/A, in order to estimate the influence of food and/or water intake on lactational performance (pup growth) and mother weight. In SHN mice, pup growth rate had negative and positive correlations with food intake and mother weight, respectively, in the 1st lactation. This indicates that food ingested is used for mother weight increase rather than for lactation. On the contrary, there was a positive correlation between pup growth rate and food intake in the 3rd lactation of SHN mice and in the 2nd lactation of GR/A mice, suggesting the preferential contribution of food to lactation. In neither SLN nor C3H/He mice apparent relations between variables were seen. These results suggest the careful choice of mouse strains for studies on nutrition and lactation.
计算了SHN、SLN、C3H/He和GR/A这四株小鼠在第1至第3次哺乳期间，哺乳期第12天幼崽生长率与第11天母体体重之间，以及母体在第4至11天之间的每日食物或水摄入量之间的偏相关系数，以评估食物和/或水摄入量对泌乳性能（幼崽生长）和母体体重的影响。在SHN小鼠中，幼崽生长率在第1次哺乳时与食物摄入量呈负相关，与母体体重呈正相关。这表明摄入的食物用于增加母体体重而非用于泌乳。相反，在SHN小鼠的第3次哺乳以及GR/A小鼠的第2次哺乳中，幼崽生长率与食物摄入量呈正相关，表明食物对泌乳有优先贡献。在SLN和C3H/He小鼠中均未观察到变量之间的明显关系。这些结果表明，在营养和泌乳研究中，要谨慎选择小鼠品系。
