局部应用后马托品眼科溶液引起的抗胆碱能谵妄：两例通过抗胆碱能放射受体测定法确诊

Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases.

作者信息

Tune L E, Bylsma F W, Hilt D C

机构信息

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

J Neuropsychiatry Clin Neurosci. 1992 Spring;4(2):195-7. doi: 10.1176/jnp.4.2.195.

DOI:10.1176/jnp.4.2.195

PMID:1627983

Abstract

The authors report two patients with prolonged metabolic delirium presumably initiated by systemic absorption of homatropine from a topical ophthalmologic solution. Anticholinergic toxicity was confirmed by muscarinic radioreceptor assay in both cases and by quantitative EEG in one case.

摘要

作者报告了两名患有长期代谢性谵妄的患者，推测是由于局部眼科溶液中的后马托品全身吸收所致。两例均通过毒蕈碱放射受体测定法确诊为抗胆碱能毒性，其中一例通过定量脑电图确诊。