Maravi Prashant, Mishra Dheerendra Kumar, Singh Amrendra, Niranjan Vijay
Department of Psychiatry, Shyam Shah Medical College, Rewa, India.
Department of Psychiatry, M.G.M. Medical College, Indore, India.
Gen Psychiatr. 2020 May 5;33(3):e100125. doi: 10.1136/gpsych-2019-100125. eCollection 2020.
Atropine is an anticholinergic drug which is used in both parental and topical routes. Topical eye-drops of atropine sulfate are used as mydriatic and cycloplegics. Parental atropine-induced delirium is well known but topical atropine eye-drop-induced delirium cases are very limited in literature. In this case report, an elderly man underwent cataract surgery and developed delirium after the use of 1% atropine sulfate eye-drops as prescribed. This case supports the notion that even atropine eye-drops can cause delirium in patients at therapeutic doses in elderly.
阿托品是一种抗胆碱能药物,可通过肠胃外和局部用药途径使用。硫酸阿托品滴眼液用作散瞳药和睫状肌麻痹剂。肠胃外使用阿托品引起谵妄是众所周知的,但局部使用阿托品滴眼液引起谵妄的病例在文献中非常有限。在本病例报告中,一名老年男性接受了白内障手术,并在按处方使用1%硫酸阿托品滴眼液后出现谵妄。该病例支持了这样一种观点,即即使是阿托品滴眼液,在治疗剂量下也可能导致老年患者出现谵妄。