Matthew Andrew G, Goldman Adam, Trachtenberg John, Robinson John, Horsburgh Sheri, Currie Kristen, Ritvo Paul
Department of Surgical Oncology, Princess Margaret Hospital, The Prostate Centre 4-922, 620 University Avenue, Toronto, Ontario, Canada M5G 2M9.
J Urol. 2005 Dec;174(6):2105-10. doi: 10.1097/01.ju.0000181206.16447.e2.
Cancer of the prostate (CAP) is one of the most common malignancies affecting North American men with about 215,000 new cases and 35,800 CAP related deaths annually. The most prevalent intervention for localized CAP is radical prostatectomy (RP) with 10-year survival rates approaching 90%. Studies of men in post-RP recovery indicate that 44% to 75% experience sexual dysfunction and more than 60% experience distress in reaction to sexual dysfunction problems. These findings are increasingly significant as prostate specific antigen testing continues to increase CAP detection rates, resulting in more and younger post-RP patients confronting sexual dysfunction.
A MEDLINE database search was performed for articles published from 1966 to September 2004.
Despite effectiveness 30% to 50% of patients who turn to sexually assistive aids after RP discontinue use within a year. This suggests that the achievement of physical responsiveness to an aid is necessary but it is not a sufficient factor in long-term sexual adaptation. Current research exploring this gap between effectiveness and ongoing use supports a broader perspective of sexual dysfunction emphasizing several factors, including perceptions of inadequacy, anxieties in regard to performance and depression in each member of the couple, overly enthusiastic expectations, partner physical/emotional readiness to resume active sex, the meaning to the couple of using a sexual aid and the quality of the nonsexual relationship of the couple.
Our findings reveal the need to explore broader strategies for improving patient coping ability and adaptation. They also point to the need to explore the role of resumed satisfying sexuality in overall quality of life following treatment.
前列腺癌(CAP)是影响北美男性的最常见恶性肿瘤之一,每年约有215,000例新发病例和35,800例与CAP相关的死亡病例。对于局限性CAP最普遍的干预措施是根治性前列腺切除术(RP),其10年生存率接近90%。对RP术后恢复阶段男性的研究表明,44%至75%的患者经历性功能障碍,超过60%的患者因性功能障碍问题而感到困扰。随着前列腺特异性抗原检测持续提高CAP的检出率,这些发现的重要性日益凸显,导致更多且更年轻的RP术后患者面临性功能障碍。
对1966年至2004年9月发表的文章进行了MEDLINE数据库检索。
尽管有效果,但30%至50%在RP术后求助于性辅助器具的患者在一年内停止使用。这表明对辅助器具产生身体反应是必要的,但在长期性适应中这并非充分因素。目前探索有效性与持续使用之间差距的研究支持对性功能障碍有更广泛的认识,强调几个因素,包括对不足的认知、对表现的焦虑以及夫妻双方各自的抑郁情绪、过度热情的期望、伴侣恢复积极性生活的身体/情感准备情况、使用性辅助器具对夫妻的意义以及夫妻非性关系的质量。
我们的研究结果表明有必要探索更广泛的策略来提高患者的应对能力和适应能力。它们还指出有必要探讨恢复满意的性生活在治疗后总体生活质量中的作用。