McDougal W Scott
Department of Urology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
J Urol. 2005 Dec;174(6):2218-20, discussion 2220. doi: 10.1097/01.ju.0000181225.31468.82.
Standard surgical methods to eradicate invasive squamous cell carcinoma of the penis often result in significant deformities. Wide local excision with skin grafting in select cases results in the preservation of normal phallic appearance and function.
Seven patients with invasive squamous cell carcinoma of the penis were treated with wide excision and resurfaced by 1 of 3 methods, namely 1) a split-thickness graft, 2) a full-thickness graft or 3) shaft skin advancement.
At 1 to 5 years of followup there was 1 local recurrence proximal to the original resection site. Local excision of recurrence resulted in no evidence of disease at 2 years of followup following repeat excision. All other patients had no local recurrence.
In select cases wide local excision with grafting or skin advancement results in a normal phallic appearance without jeopardizing cancer control.
根除阴茎浸润性鳞状细胞癌的标准手术方法常常会导致明显畸形。在特定病例中，广泛局部切除并植皮可保留正常阴茎外观和功能。
7例阴茎浸润性鳞状细胞癌患者接受了广泛切除，并用以下3种方法之一进行创面修复，即1）断层皮片移植，2）全厚皮片移植或3）阴茎体皮肤推进。
随访1至5年，在原切除部位近端有1例局部复发。复发行局部切除后，随访2年无疾病证据。所有其他患者均无局部复发。
在特定病例中，广泛局部切除并植皮或进行皮肤推进可使阴茎外观正常，且不影响癌症控制。
