Li N, Tuomilehto J, Dowse G, Alberti K G, Zimmet P, Min Z, Chitson P, Gareeboo H, Chonghua Y, Fareed D
Beijing Heart Lung and Blood Vessel Medical Centre, China.
BMJ. 1992 Jun 20;304(6842):1596-601. doi: 10.1136/bmj.304.6842.1596.
To compare the prevalence of electrocardiographic abnormalities and to evaluate the association between these abnormalities and the levels of coronary heart disease among Chinese living in different environments.
Cross sectional surveys.
Beijing, China, and the island of Mauritius.
Random samples of people aged 35-64 years in Beijing (621 men, 642 women) in 1984 and in Mauritius among Chinese (137 men, 130 women) and non-Chinese (1265 men, 1432 women) in 1987.
Prevalence of electrocardiographic abnormalities suggesting coronary heart disease and of associated risk factors.
Prevalence of electrocardiographic abnormalities suggesting coronary heart disease was significantly lower in Beijing (4.0%) than in Mauritian Chinese (24.3%) and Mauritian non-Chinese (24.5%). Mean serum concentrations of total and non-high density lipoprotein cholesterol were lower in Beijing Chinese than in Mauritian Chinese, but smoking and hypertension were slightly more prevalent. Overall, men with electrocardiographic abnormalities had higher risk factor levels than those with a normal electrocardiogram regardless of ethnic origin.
The prevalence of coronary heart disease and associated risk factors was different among Chinese living in two different environments: in Beijing in the People's Republic of China and in Mauritius. Chinese, who traditionally have a very low frequency of coronary heart disease, are by no means protected against coronary heart disease and other non-communicable diseases. Therefore, primary prevention of coronary heart disease is a major challenge for preventive medicine in China, as well as in many other developing countries.
比较不同居住环境下中国人心电图异常的患病率,并评估这些异常与冠心病水平之间的关联。
横断面调查。
中国北京和毛里求斯岛。
1984年在北京随机抽取的35 - 64岁人群样本(621名男性,642名女性),以及1987年在毛里求斯的华裔(137名男性,130名女性)和非华裔(1265名男性,1432名女性)。
提示冠心病的心电图异常患病率及相关危险因素。
提示冠心病的心电图异常患病率在北京(4.0%)显著低于毛里求斯华裔(24.3%)和毛里求斯非华裔(24.5%)。北京华人的总胆固醇和非高密度脂蛋白胆固醇的平均血清浓度低于毛里求斯华人,但吸烟和高血压的患病率略高。总体而言,无论种族如何,心电图异常的男性其危险因素水平高于心电图正常者。
生活在中华人民共和国北京和毛里求斯这两种不同环境下的中国人,冠心病及相关危险因素的患病率存在差异。传统上冠心病发病率极低的中国人,绝不能免受冠心病和其他非传染性疾病的影响。因此,冠心病的一级预防对中国以及许多其他发展中国家的预防医学来说是一项重大挑战。