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[高血压脑病:伴中线移位的脑水肿的鉴别诊断]

[Hypertensive encephalopathy: differential diagnosis of brain edema with midline shift].

作者信息

Nagel S, Köhrmann M, Huttner H B, Schwab S

机构信息

Neurologische Klinik, Universität Heidelberg.

出版信息

Nervenarzt. 2006 Apr;77(4):466-9. doi: 10.1007/s00115-005-1995-5.

DOI:10.1007/s00115-005-1995-5
PMID:16283152
Abstract

Hypertensive encephalopathy is a severe complication of hypertensive crisis or malignant hypertonia. We report a case with grave clinical and radiological features. The patient was comatose, with pupillary dysfunction, and initial CT suggested a local intracranial mass with edema. Cranial MRI showed almost completely hyperintensive supratentorial white matter, with edema and midline shift, and hypertensities in cerebellum and brainstem. The patient recovered, and the radiological findings improved after antihypertensive therapy. Hypertensive encephalopathy may be differentiated by MRI, manifests acutely, and is potentially reversible when adequate therapy is rapidly performed.

摘要

高血压脑病是高血压危象或恶性高血压的严重并发症。我们报告一例具有严重临床和放射学特征的病例。患者昏迷,伴有瞳孔功能障碍,最初的CT提示局部颅内肿块伴水肿。头颅MRI显示幕上白质几乎完全呈高信号,伴有水肿和中线移位,小脑和脑干也有高信号。患者康复,降压治疗后放射学表现改善。高血压脑病可通过MRI鉴别,起病急,若迅速进行适当治疗则可能可逆。

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本文引用的文献

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Hyperperfusion encephalopathies: hypertensive encephalopathy and related conditions.高灌注性脑病:高血压性脑病及相关病症。
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Hypertensive encephalopathy, reversible occipitoparietal encephalopathy, or reversible posterior leukoencephalopathy: three names for an old syndrome.高血压脑病、可逆性枕叶顶叶脑病或可逆性后部白质脑病:一种古老综合征的三个名称。
J Child Neurol. 1999 May;14(5):277-81. doi: 10.1177/088307389901400502.
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A reversible posterior leukoencephalopathy syndrome.可逆性后部白质脑病综合征
N Engl J Med. 1996 Feb 22;334(8):494-500. doi: 10.1056/NEJM199602223340803.
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The blood-brain barrier and cerebral blood flow in acute hypertension.急性高血压时的血脑屏障与脑血流量
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Hypertensive encephalopathy: findings on CT, MR imaging, and SPECT imaging in 14 cases.高血压脑病:14例患者的CT、磁共振成像及单光子发射计算机断层扫描成像表现
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