Prather J L, Long J M, van Heertum R, Hardman J
Br J Radiol. 1975 Jan;48(565):10-5. doi: 10.1259/0007-1285-48-565-10.
Single case reports of multicentric glioblastoma multiforme and multifocal glioblastoma multiforme tumours are presented. Multicentric glioblastoma multiforme tumours are those which have no macroscopic or microscopic connection. Multifocal gliomatous tumours, on the other hand, are those with either gross or microsopic continuity or evidence of cerebral spinal fluid spread and/or local metastases. The cerebral scintigram findings, cerebral angiogram studies and pathological description of these entities are presented. These lesions may be mistaken for metastases. In patients with multiple cerebral lesions multiple primary malignancies of brain should be considered when there is no clinical or radiographical evidence for extracranial primary neoplasms.
本文报告了多中心性多形性胶质母细胞瘤和多灶性多形性胶质母细胞瘤的单病例报告。多中心性多形性胶质母细胞瘤是指那些在宏观或微观上没有联系的肿瘤。另一方面，多灶性胶质瘤是指那些具有大体或微观连续性或有脑脊液播散和/或局部转移证据的肿瘤。本文还介绍了这些病变的脑闪烁显像结果、脑血管造影研究和病理描述。这些病变可能被误诊为转移瘤。在患有多个脑病变的患者中，当没有颅外原发性肿瘤的临床或影像学证据时，应考虑脑的多个原发性恶性肿瘤。
