Wright Mathew W, Eyre Tina A, Lush Michael J, Povey Sue, Bruford Elspeth A
HUGO Gene Nomenclature Committee, The Galton Laboratory, Department of Biology, University College London, Wolfson House, 4, Stephenson Way, London, UK.
Mamm Genome. 2005 Nov;16(11):827-8. doi: 10.1007/s00335-005-0103-2. Epub 2005 Nov 11.
The HGNC Comparison of Orthology Predictions search tool, HCOP (http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/hcop.pl ), enables users to compare predicted human and mouse orthologs for a specified gene, or set of genes, from either species according to the ortholog assertions from the Ensembl, HGNC, Homologene, Inparanoid, MGI and PhIGs databases. Users can assess the reliability of the prediction from the number of these different sources that identify a particular orthologous pair. HCOP provides a useful one-stop resource to summarise, compare and access various sources of human and mouse orthology data.
HGNC直系同源预测比较搜索工具HCOP(http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/hcop.pl )可让用户根据Ensembl、HGNC、Homologene、Inparanoid、MGI和PhIGs数据库中的直系同源断言,比较指定基因或一组基因在人类和小鼠之间预测的直系同源基因,这些基因来自任一物种。用户可以根据识别特定直系同源对的不同来源数量来评估预测的可靠性。HCOP提供了一个有用的一站式资源,用于汇总、比较和访问人类和小鼠直系同源数据的各种来源。