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补骨脂素-紫外线A疗法、自然杀伤细胞功能不全或阳光照射增强所致银屑病患者的多发性癌?

Multiple carcinoma in patients with psoriasis caused by psoralen-ultraviolet A therapy, natural killer cell insufficiency, or intensified sun exposure?

作者信息

Rubins A Y, Branta D K, Hartmane I V, Rajevska A S, Gutmane R A, Lielbriedis Y M

机构信息

Department of Dermatology, Latvian Medical Academy, Riga.

出版信息

Cutis. 1992 Jun;49(6):430-2.

PMID:1628511
Abstract

A case is presented of a patient with psoriasis in whom squamous cell carcinoma most likely occurred due to the interaction of various factors (psoralen-ultraviolet A therapy, sun exposure, and suppression of natural killer cell function). Therapy consisted of 1 mg/kg/daily of etretinate (Tegison), which resulted in clearing of psoriatic lesions in one month's time. New carcinomas did not develop and natural killer function improved.

摘要

本文报告了一例银屑病患者,其鳞状细胞癌很可能是由多种因素(补骨脂素-紫外线A疗法、日晒及自然杀伤细胞功能受抑制)相互作用所致。治疗方法为每日口服1mg/kg依曲替酯(银屑灵),一个月后银屑病皮损消退。未出现新的癌肿,自然杀伤功能有所改善。

相似文献

1
Multiple carcinoma in patients with psoriasis caused by psoralen-ultraviolet A therapy, natural killer cell insufficiency, or intensified sun exposure?补骨脂素-紫外线A疗法、自然杀伤细胞功能不全或阳光照射增强所致银屑病患者的多发性癌?
Cutis. 1992 Jun;49(6):430-2.
2
[Development of multiple spinocellular cancer of the skin in a patient with psoriasis].
Vestn Dermatol Venerol. 1989(3):72-4.
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Risk of cutaneous carcinoma in patients treated with oral methoxsalen photochemotherapy for psoriasis.口服甲氧沙林光化学疗法治疗银屑病患者发生皮肤癌的风险。
N Engl J Med. 1979 Apr 12;300(15):809-13. doi: 10.1056/NEJM197904123001501.
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Nodular malignant melanoma and multiple squamous cell carcinomas in a patient treated by photochemotherapy for psoriasis.一名接受光化学疗法治疗银屑病的患者出现结节性恶性黑色素瘤和多发性鳞状细胞癌。
Br Med J (Clin Res Ed). 1984 Dec 1;289(6457):1498. doi: 10.1136/bmj.289.6457.1498.
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Skin carcinomas and treatment with photochemotherapy (PUVA).皮肤癌与光化学疗法(补骨脂素加紫外线A)治疗
Acta Derm Venereol. 1983;63(3):223-6.
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[Great risk of skin cancer in patients with transplanted organs. Sun is the most dangerous enemy].[器官移植患者患皮肤癌的风险极高。阳光是最危险的敌人]
Lakartidningen. 2000 Oct 25;97(43):4822-4.
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[Photochemotherapy--psoralen + UV-A (PUVA)--increased risk of cancer?].[光化学疗法——补骨脂素加紫外线A(PUVA)——会增加患癌风险吗?]
Tidsskr Nor Laegeforen. 1993 Jan 20;113(2):200-1.
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Effects of systemic etretinate treatment on natural cytotoxicity, immune angiogenesis and neutrophil adherence in patients with various forms of psoriasis.全身性阿维A治疗对各种类型银屑病患者自然细胞毒性、免疫血管生成和中性粒细胞黏附的影响。
Arch Immunol Ther Exp (Warsz). 1989;37(3-4):459-64.
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Carcinogenic effect of sequential artificial sunlight and UV-A irradiation in hairless mice. Consequences for solarium 'therapy'.
Arch Dermatol. 1983 Aug;119(8):641-3.
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[Cutaneous carcinoma and papillomavirus 5. Discovered during prolonged UVA photochemotherapy].[皮肤癌与乳头瘤病毒5. 在长期UVA光化学疗法期间发现]
Ann Dermatol Venereol. 1994;121(6-7):496-8.

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