Wessling-Assmann Kathrin, Traupe H, Bonsmann G, Metze D
Universitäts-Hautklinik Münster.
J Dtsch Dermatol Ges. 2003 Apr;1(4):297-9. doi: 10.1046/j.1610-0387.2003.02017.x.
Subcutaneous fat necrosis presents as red-to-bluish, indolent, well-circumscribed, subcutaneous nodules and plaques, unusually in healthy infants. Histologically, a lobular panniculitis with a mixed inflammatory infiltrate is seen. Characteristic crystalloid structures can be found within some of the lipocytes and, most prominently, within macrophages. This rarely diagnosed skin disease is harmless and self-limited, yet the associated hypercalcaemia has a high complication rate.
皮下脂肪坏死表现为红色至蓝色、无痛性、边界清晰的皮下结节和斑块，多见于健康婴儿。组织学上可见小叶性脂膜炎伴混合性炎性浸润。在一些脂肪细胞内，尤其是巨噬细胞内可发现特征性的晶体结构。这种罕见的皮肤病无害且具有自限性，但其相关的高钙血症并发症发生率很高。
