Divisions of Nephrology and Endocrinology, Department of Paediatrics, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Paediatr Int Child Health. 2021 Aug;41(3):221-225. doi: 10.1080/20469047.2021.1883960. Epub 2021 Mar 14.
Subcutaneous fat necrosis (SFN) in the newborn is a form of panniculitis which presents with erythematous nodules and indurated plaques. Severe life-threatening hypercalcaemia can occur as a late complication. A 2-month-old girl presented with severe hypercalcaemia and acute renal injury as a complication of SFN. She was admitted to hospital with the chief complaint of failure to thrive. She had a history of therapeutic hypothermia. After successful treatment of the hypercalcaemia with bisphosphonates, the acute renal injury recovered spontaneously. In neonates with SFN, acute renal injury is a rare complication of hypercalcaemia. Timely prevention of the complications of hypercalcaemia in SFN is essential.
新生儿皮下脂肪坏死（SFN）是一种脂膜炎，表现为红斑性结节和硬结性斑块。严重的威胁生命的高钙血症可能是晚期并发症。一名 2 个月大的女婴因 SFN 并发严重高钙血症和急性肾损伤而入院。她因发育不良而入住医院。她有接受治疗性低温治疗的病史。高钙血症经双膦酸盐成功治疗后，急性肾损伤自行恢复。在患有 SFN 的新生儿中，急性肾损伤是高钙血症的罕见并发症。及时预防 SFN 高钙血症的并发症至关重要。
