Taylor Richard J K, Reid Mark, Foot Jonathan, Raw Steven A
Department of Chemistry, University of York, Heslington, York YO10 5DD , United Kingdom.
Acc Chem Res. 2005 Nov;38(11):851-69. doi: 10.1021/ar050113t.
"One-pot" processes in which alcohol oxidations are combined with further elaboration of the carbonyl intermediate are reviewed. Sequential processes are briefly discussed, but most attention is centered on tandem processes; that is, oxidations carried out in the presence of a nucleophilic trapping agent, rather than those in which the trapping agent is added after the oxidation is complete. As part of this Account, a comprehensive review of the discovery of tandem oxidation processes (TOP) will be given together with applications in alkene-forming reactions, cyclopropanations, and imine, oxime, amine, and heterocycle formation.
本文综述了将醇氧化与羰基中间体的进一步转化相结合的“一锅法”工艺。对连续工艺进行了简要讨论，但重点关注串联工艺；也就是说，氧化反应是在亲核捕获剂存在的情况下进行的，而不是在氧化反应完成后再添加捕获剂的情况。作为本综述的一部分，将对串联氧化工艺（TOP）的发现进行全面回顾，并介绍其在烯烃形成反应、环丙烷化反应以及亚胺、肟、胺和杂环形成反应中的应用。
