Dubois Bertrand, Caux Christophe
INSERM U404 "Immunité et Vaccination", IFR-128 Biosciences Lyon Gerland, 21 avenue Tony Garnier, 69365 Lyon Cedex 07, France.
Immunity. 2005 Nov;23(5):463-4. doi: 10.1016/j.immuni.2005.10.005.
The contribution of dendritic cells (DCs) to antibody responses through antigen-unspecific B cell costimulation is well documented. now demonstrate that the ITIM-bearing FcgammaRIIB allows DCs to recycle internalized native antigen (Ag) for presentation to B cells, a process that might be critical for the initiation of humoral responses.