Badhwar Nitish, Kalman Jonathan M, Sparks Paul B, Kistler Peter M, Attari Mehran, Berger Marcie, Lee Randall J, Sra Jasbir, Scheinman Melvin M
University of California, San Francisco, San Francisco, California 94143, USA.
J Am Coll Cardiol. 2005 Nov 15;46(10):1921-30. doi: 10.1016/j.jacc.2005.07.042. Epub 2005 Oct 24.
We sought to describe the electrophysiological features and long-term outcome after radiofrequency catheter ablation (RFCA) of atrial tachycardia (AT) arising from the coronary sinus (CS) musculature.
Atrial tachycardia requiring RFCA deep within the CS has been described in isolated case reports. However, the mechanism and exact site of origin of this tachycardia have not been well elucidated.
The study included 8 patients (5 men) of a consecutive series of 283 patients undergoing RFCA for focal AT.
In sinus rhythm, a discrete potential (P) was noted after the CS atrial electrogram and during tachycardia, the CS (P) preceded the surface P-wave by 30 to 50 ms. The CS (P) always preceded the earliest electrogram in the left atrium (LA). Three-dimensional electroanatomical mapping was available in four patients, and in one case it showed earliest activation in the CS with rapid spread to the proximal CS and then to the LA. Ablation of the AT initially attempted from the earliest site in the LA in three patients was unsuccessful. In all patients the tachycardia was safely and successfully ablated at a site 3.6 cm within the CS. There has been no recurrence over a follow-up of 37 +/- 13 months.
Focal AT emanating deep within the CS musculature can be recognized by a discrete potential associated with the CS atrial signal both during sinus rhythm and tachycardia. Long-term success without complications can be accomplished by ablating within the CS in close proximity to the CS (P).
我们试图描述起源于冠状窦(CS)肌组织的房性心动过速(AT)经射频导管消融(RFCA)后的电生理特征和长期预后。
在个别病例报告中曾描述过需要在CS深部进行RFCA的房性心动过速。然而,这种心动过速的机制和确切起源部位尚未得到充分阐明。
该研究纳入了连续283例行局灶性AT射频消融术患者中的8例(5例男性)。
在窦性心律时,在CS心房电图之后可记录到一个离散电位(P),在心动过速时,CS(P)比体表P波提前30至50毫秒。CS(P)总是先于左心房(LA)最早的电图。4例患者可行三维电解剖标测,其中1例显示CS最早激动,并迅速扩散至CS近端,然后至LA。3例患者最初尝试从LA最早部位消融AT未成功。所有患者的心动过速均在CS内距CS(P)3.6 cm处安全成功消融。随访37±13个月无复发。
起源于CS肌组织深部的局灶性AT在窦性心律和心动过速时均可通过与CS心房信号相关的离散电位识别。在靠近CS(P)的CS内进行消融可实现无并发症的长期成功。